香叶基香叶基焦磷酸合成酶在肺鳞状细胞癌中的表达及临床意义
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王鑫, 王晓霞, 李彦庆, 郑永鑫, 乌杰, 任猛, 贾向东, 许天祥
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Expression and clinical significance of geranylgeranyl diphosphate synthase1 (GGPS1) in lung squamous cell carcinoma
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WANG Xin, WANG Xiaoxia, LI Yanqing, ZHENG Yongxin, WU Jie, REN Meng, JIA Xiangdong, XU Tianxiang
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表2 GGPS1表达水平与LUSC临床病理特征的相关性
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Tab 2 Correlation between GGPS1 expression level and clinicopathological characteristics of LUSC
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| Characteristic | Total/n | GGPS1/n(%) | χ2 value | P value |
|---|
| Low expression | High expression |
|---|
| Gender | | | | 1.213 | 0.271 | | Male | 84 | 41 (48.8) | 43 (51.2) | | | | Female | 6 | 1 (16.7) | 5 (83.3) | | | | Age | | | | 0.003 | 0.955 | | ≤64 years old | 49 | 23 (46.9) | 26 (53.1) | | | | >64 years old | 41 | 19 (46.3) | 22 (53.7) | | | | History of smoking | | | | 2.691 | 0.101 | | No | 41 | 23 (56.1) | 18 (43.9) | | | | Yes | 49 | 19 (38.8) | 30 (61.2) | | | | Tumor location | | | | 0.984 | 0.321 | | Left | 40 | 21 (52.5) | 19 (47.5) | | | | Right | 50 | 21 (42.0) | 29 (58.0) | | | | Tumor size | | | | 10.247 | 0.001 | | ≤3 cm | 26 | 19 (73.1) | 7 (26.9) | | | | >3 cm | 64 | 23 (35.9) | 41 (64.1) | | | | Lymph node metastasis | | | | 7.626 | 0.006 | | No | 46 | 28 (60.9) | 18 (39.1) | | | | Yes | 44 | 14 (31.8) | 30 (68.2) | | | | TNM stage | | | | 8.935 | 0.003 | | Ⅰ~Ⅱ | 47 | 29 (61.7) | 18 (38.3) | | | | Ⅲ~Ⅳ | 43 | 13 (30.2) | 30 (69.8) | | |
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