香叶基香叶基焦磷酸合成酶在肺鳞状细胞癌中的表达及临床意义

王鑫, 王晓霞, 李彦庆, 郑永鑫, 乌杰, 任猛, 贾向东, 许天祥

Expression and clinical significance of geranylgeranyl diphosphate synthase1 (GGPS1) in lung squamous cell carcinoma

WANG Xin, WANG Xiaoxia, LI Yanqing, ZHENG Yongxin, WU Jie, REN Meng, JIA Xiangdong, XU Tianxiang

表3 影响LUSC患者OS的Cox回归模型

Tab 3 Cox regression model affecting OS of LUSC patients

Variable Univariate analysis Multivariate analysis HR 95%CI P value HR 95%CI P value Gender 0.652 0.232‒1.837 0.419 Age 0.631 0.336‒1.185 0.152 History of smoking 2.054 1.054‒4.003 0.034 2.045 1.024‒4.086 0.043 Tumor location 0.878 0.468‒1.648 0.686 Tumor size 2.751 1.151‒6.574 0.023 1.621 0.639‒4.114 0.309 Lymph node metastasis 3.116 1.577‒6.157 0.001 4.039 1.257‒12.983 0.019 TNM stage 2.399 1.246‒4.619 0.009 0.473 0.147‒1.523 0.210 GGPS1 expression 3.872 1.834‒8.176 0.000 2.867 1.316‒6.242 0.008