多发伤患者血清高迁移率族蛋白B1及可溶性髓样细胞触发受体-1水平变化及预后意义

王桂杰, 杜传冲, 陆叶, 赵健, 沈勰, 金冬林, 耿佳财

Changes of serum high mobility group box 1 and soluble triggering receptor expressed on myeloid cells-1 in patients with multiple injuries and their prognostic significance

WANG Guijie, DU Chuanchong, LU Ye, ZHAO Jian, SHEN Xie, JIN Donglin, GENG Jiacai

表1 不同严重程度多发伤患者HMGB1、sTREM-1水平比较

Tab 1 Comparison of HMGB1 and sTREM-1 levels in patients with multiple injuries of different severity

Variable	Light injury group (n=24)	Grave injury group (n=58)	Severe injury group (n=10)	P value^③	P value^④	P value^⑤
HMGB1/(ng·mL^-1)^①
24 h	2.47±0.61	2.86±0.65	2.99±0.52	0.013	0.030	0.531
72 h	3.12±0.73	3.57±0.66	4.22±0.31	0.006	0.000	0.005
7 d	3.63±0.83	4.19±0.77	4.96±0.35	0.003	0.000	0.004
sTREM-1/(ng·mL^-1)^②
24 h	11.71±3.00	13.43±2.65	15.38±1.95	0.010	0.000	0.037
72 h	12.77±3.47	14.46±2.74	16.51±1.99	0.017	0.001	0.041
7 d	5.52±1.24	6.47±1.25	6.72±1.20	0.006	0.015	0.463