沙蟾毒精抗癌活性及相关机制的研究进展

白雯会, 沈淑坤, 吴英理

Research progress in the anti-cancer activity and related mechanisms of arenobufagin

BAI Wenhui, SHEN Shukun, WU Yingli

表1 经ARE处理24 h的不同细胞的IC50

Tab 1 IC50 of different cells treated with ARE for 24 h

Type of tumor Type of cell IC50 Pancreatic cancer Panc-1 10 nmol/L[11] AsPC-1 1 nmol/L[11] SW 1990 9.9 nmol/L[12] BxPC-3 48.72 nmol/L[5] Lung cancer A549 10 nmol/L[13-14] Breast cancer MCF 7 485 nmol/L[10,15] Esophageal carcinoma Eca-109 0.8 μmol/L[8] TE-11 3.6 μmol/L[8] Glioma U-87 MG 10.3 nmol/L[9] Cervical cancer HELA 23 nmol/L[10] Colon cancer HT-29 25 nmol/L[10]