肺癌恶性胸腔积液来源肿瘤细胞的小鼠PDX模型构建及实验验证

王梦婷, 陈怡楠, 轩辕欣阳, 袁海花

Construction and experimental validation of mouse PDX model by malignant pleural effusion-derived tumor cells from lung cancer

WANG Mengting, CHEN Yinan, XUANYUAN Xinyang, YUAN Haihua

图4 肺癌MPE来源肿瘤细胞小鼠PDX模型的组织病理学验证 Note： A. The growth of subcutaneous MPE-PDX in NOD/SCID mice (left); P4 generation PDX with H-E staining (×200) (right). B. IHC testing (×200) of transplanted tumors compared with clinical samples of MPE tumor cells from patients.

Fig 4 Histopathological validation on mouse PDX of tumor cells derived from MPE of lung cancer