肺癌恶性胸腔积液来源肿瘤细胞的小鼠PDX模型构建及实验验证
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王梦婷, 陈怡楠, 轩辕欣阳, 袁海花
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Construction and experimental validation of mouse PDX model by malignant pleural effusion-derived tumor cells from lung cancer
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WANG Mengting, CHEN Yinan, XUANYUAN Xinyang, YUAN Haihua
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表1 肺癌MPE来源已建成PDX信息
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Tab 1 Information of established MPE-PDX
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| No. | Histologic subtype | Tumor marker | TNM stage | Mutation |
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| CK-7 | TTF1 | Napsin A | p40 |
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| LC001 | AD | / | / | / | / | TxN3M0 | / | | LC002 | AD | + | + | + | / | TxN3M1 | EGFR L858R | | LC003 | NSCLC | / | / | / | / | T4N1M1 | / | | LC004 | AD | + | - | + | / | TxN3M1 | EGFR Exon20ins | | LC005 | AD | / | / | / | / | rTNM | EGFR L858R | | LC006 | AD | / | / | / | / | T4N3M1c | ALK, ROS1 | | LC007 | AD | + | + | + | / | T1N0M0 | PD-L1, TP53 | | LC008 | AD | / | / | / | / | TxN1M2 | EGFR Exon19del | | LC009 | AD | + | + | + | / | TxN1M1c | EGFR Exon18 | | LC010 | NSCLC | / | + | / | + | TxN3M1 | No mutation | | LC011 | NSCLC | / | / | / | / | TxN3M1 | / | | LC012 | SCC | / | / | / | / | T3N0M1c | / | | LC013 | NSCLC | + | - | - | - | TxN3M1c | / |
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