星形胶质细胞在噪声损伤后小鼠耳蜗核突触修复中的作用

周卫军, 刘思迪, 蔡瑞捷, 刘宏超, 王美建, 吴皓, 刘辉辉, 汪照炎

Role of astrocytes in the repair of auditory synapses in the cochlear nucleus after noise damage

ZHOU Weijun, LIU Sidi, CAI Ruijie, LIU Hongchao, WANG Meijian, WU Hao, LIU Huihui, WANG Zhaoyan

图4 噪声暴露导致耳蜗核星形胶质细胞激活 Note： A. Immunofluorescence staining (GFAP) of cochlear nucleus astrocytes after noise exposure. B. Immunofluorescence staining (×63) of cochlear nucleus auditory nerve synapses and astrocytes after noise exposure, showing auditory nerve synapses (Vglut1), astrocytes (GFAP), and cell nuclei (DAPI). C. Western blotting results of cochlear nucleus after noise exposure. ①P=0.001, ②P=0.130, ③P=0.929, ④P=0.019, ⑤P=0.048, compared with the D0 (control) group.

Fig 4 Noise exposure leads to the activation of cochlear nucleus astrocytes