成骨细胞条件性视黄酸信号失活小鼠模型的构建与验证

孙思远, 刘媛琪, 崔怡雯, 黄紫晗, 梅李, 代庆刚, 江凌勇

Generation and validation of the conditional osteoblast-specific retinoic acid signaling inhibition mouse model

SUN Siyuan, LIU Yuanqi, CUI Yiwen, HUANG Zihan, MEI Li, DAI Qinggang, JIANG Lingyong

图5 OsxCre;Rosa26dn/dn 小鼠颅颌面骨畸形分析 Note： A. The three-dimensional (3D) reconstruction of the Micro-CT of 6-week-old mouse skulls. B. Bone segmentation of the mouse skulls. C. Analysis of the length of skulls. D. Analysis of the width of skulls. E. Analysis of the length of mandibles. F. The 3D reconstruction of the craniofacial bones. G. Analysis of the volume of craniofacial bones, including mandible, nasal bone, frontal bone, parietal bone, interparietal bone, occipital bone, premaxilla, and maxilla.

Fig 5 Craniofacial skeletal deformity analysis of OsxCre;Rosa26dn/dn mice