结直肠癌中自然杀伤细胞表型及功能初探

冯昫皎, 刘健悦, 戚炀炀, 孙晶, 沈蕾

Phenotype and function of NK cell in colorectal cancer

FENG Xujiao, LIU Jianyue, QI Yangyang, SUN Jing, SHEN Lei

图3 CD38highNK细胞在肿瘤组织中显著减少 Note： A. Representative flow cytometry analysis and percentage of CD38highNK cells in normal and tumor tissues (n=25). B. Representative flow cytometry analysis of the expression of CD16, NKp46, CD57, CD94, HLA-DR and CD158a in CD38highNK cells and CD38lowNK cells in tumor tissues. C. The expression levels of CD16, NKp46, CD57, CD94, HLA-DR and CD158a in CD38highNK cells and CD38lowNK cells in tumor tissues (n=25). ①P=0.003, ②P=0.000.

Fig 3 CD38highNK cells were dramatically reduced in tumor tissues