钙离子转运ATP酶B2杂合突变导致小鼠渐进性前庭功能障碍

刘祎晴, 金晨曦, 冯宝怡, 成桢哲, 孙怡琳, 郑晓飞, 董庭婷, 吴皓, 陶永

Atp2b2 Oblivion heterozygous mutation causes progressive vestibular dysfunction in mice

LIU Yiqing, JIN Chenxi, FENG Baoyi, CHENG Zhenzhe, SUN Yilin, ZHENG Xiaofei, DONG Tingting, WU Hao, TAO Yong

图4 2月龄Wt组及Obl/+组小鼠VsEP、VEMP及行为学实验 Note： A. VsEP waveform. B. VsEP threshold comparison. C. P1N1 amplitude comparison. D. P1 latency comparison. E. VEMP waveform. F. VEMP threshold comparison. G. Latency to fall from the rotary rod within 300 s. H. Time to pass 80 cm balance beam. ①P=0.000, ②P=0.027, ③P=0.018.

Fig 4 VsEP, VEMP and behavioral tests of 2-month-old mice in the Wt group and the Obl/+ group