PRMT6促进乳腺癌细胞的增殖和迁移

韩依杉, 徐梓淇, 陶梦玉, 范广建, 余波

PRMT6 promotes the proliferation and migration of breast cancer cells

HAN Yishan, XU Ziqi, TAO Mengyu, FAN Guangjian, YU Bo

图2 沉默 PRMT6 抑制乳腺癌细胞的增殖 Note： A/B. Transfection efficiency of PRMT6 siRNAs in MDA-MB-231 cell line (A) and MCF-7 cell line (B) verified by Western blotting. C/D. Transfection efficiency of PRMT6 siRNAs in MDA-MB-231 cell line (C) and MCF-7 cell line (D) detected by qRT-PCR. E/F. Effect of PRMT6 siRNA on the proliferation of MDA-MB-231 and MCF-7 cells detected by CCK-8 assay. G. Representative images of colony formation in PRMT6 knock down MDA-MB-231 cells and MCF-7 cells. H. Colony formation efficiency of MDA-MB-231 and MCF-7 cell lines after 10-d incubation.

Fig 2 Deletion of PRMT6 suppressed breast cancer cell proliferation