分选链接蛋白1抑制结直肠癌细胞增殖和迁移的作用和机制研究

钱立恒, 温凯玲, 廖颖娜, 李书鑫, 聂惠贞

Study on the effect and mechanism of sorting nexin 1 on inhibiting the proliferation and migration of colorectal cancer cells

QIAN Liheng, WEN Kailing, LIAO Yingna, LI Shuxin, NIE Huizhen

图1 SNX家族在人类肿瘤中的表达情况 Note： STAD—stomach adenocarcinoma; LIHC—liver hepatocellular carcinoma; BRCA—breast invasive carcinoma; HNSC—head and neck squamous cell carcinoma; ESCA—esophageal carcinoma; COAD—colon adenocarcinoma; READ—rectum adenocarcinoma; LGG—brain lower grade glioma; GBM—glioblastoma multiforme; THYM—thymoma; DLBC—lymphoid neoplasm diffuse large B-cell lymphoma; PAAD—pancreatic adenocarcinoma; CHOL—cholangiocarcinoma; TGCT—testicular germ cell tumor; LUAD—lung adenocarcinoma; LUSC—lung squamous cell carcinoma; KIRP—kidney renal papillary cell carcinoma; KIRC—kidney renal clear cell carcinoma; SARC—sarcoma; PCPG—pheochromocytoma and paraganglioma; THCA—thyroid carcinoma; SKCM—skin cutaneous melanoma; OV—ovarian serous cystadenocarcinoma; BLCA—bladder urothelial carcinoma; CESC—cervical squamous cell carcinoma and endocervical adenocarcinoma; UCS—uterine carcinosarcoma; UCEC—uterine corpus endometrial carcinoma; KICH—kidney chromophobe; ACC—adrenocortical carcinoma; PRAD—prostate adenocarcinoma.

Fig 1 Expression levels of SNX family in human cancers