非经典型多梳抑制复合物1.6的电镜结构分析

蔡单, 黄晶

Electron microscopic study of the non-canonical polycomb repressive complex 1.6

CAI Dan, HUANG Jing

图1 PRC1.6七元复合物成分与蛋白结构域组成示意图 Note： A. The schematic diagram of the PRC1.6 heptameric complex depicts its ability to recognize and modify nucleosomes. B. Domain organization of human PRC1.6 heptameric complex. RING—really interesting new gene; RAWUL—ring finger and WD40-associated ubiquitin-like; ZnF—zinc finger; MBT—malignant brain tumor; CD—chromodomain; CSD—chromodomain-shadow; DBD—DNA binding domain; LZ—leucine zipper; MB—marked-box; CC—coiled coil; Ub-ubiquitin.

Fig 1 Schematic diagram of components and domain organization of the PRC1.6 heptameric complex