肿瘤坏死因子-α在新型冠状病毒感染合并肾损伤中的作用

PANDIT Roshan, 卢君瑶, 何立珩, 包玉洁, 季萍, 陈颖盈, 许洁, 王颖

Role of tumor necrosis factor-α in coronavirus disease 2019-associated kidney injury

PANDIT Roshan, LU Junyao, HE Liheng, BAO Yujie, JI Ping, CHEN Yingying, XU Jie, WANG Ying

表2 COVID-19患者外周免疫细胞计数比较

Tab 2 Comparisons of peripheral immune cell numbers in COVID-19 patients

Item Sex Age group Severity of pneumonia Male Female P value ≤60 years >60 years P value Moderate Severe P value WBC/(109‧L-1) 8.82±4.40 6.00±3.50 0.065 5.67±2.40 7.92±4.40 0.355 8.05±4.90 7.39±3.80 0.910 Neutrophil/% 77.06±14.70 77.92±10.90 0.808 77.57±6.40 77.39±13.80 0.437 72.86±16.10 80.88±9.30 0.100 Lymphocyte/% 15.21±13.50 15.32±9.50 0.830 15.57±4.80 15.22±12.60 0.355 19.96±15.50 11.67±6.80 0.060 Monocyte/% 6.74±3.60 5.82±2.30 0.368 6.40±4.20 6.36±3.10 0.721 6.19±2.80 6.50±3.50 0.734 Platelet/(109‧L-1) 211.95±100.80 199.66±90.50 0.775 282.75±139.40 197.78±87.50 0.585 202.25±54.00 210.57±119.30 1.000 CD3+ T cell/µL-1 519.81±359.10 538.20±335.50 0.914 719.00±190.50 504.03±354.10 0.078 641.50±398.40 440.23±277.30 0.050 CD4+ T cell/µL-1 255.63±143.80 318.60±237.90 0.722 386.75±127.70 268.36±190.60 0.156 309.62±152.40 259.47±211.10 0.137 CD8+ T cell/µL-1 242.59±278.90 198.73±148.20 0.643 323.75±223.00 212.81±234.80 0.261 298.18±321.20 168.90±113.60 0.104 B cell/µL-1 491.95±1 832.50 133.66±124.40 0.734 159.50±119.20 369.39±1 496.60 0.463 673.25±2 140.70 97.90±82.10 0.122 NK cell/µL-1 154.63±118.50 145.60±224.80 0.205 123.00±113.40 154.36±173.30 0.642 155.93±124.90 147.19±196.00 0.263