孕期超加工食品摄入与妊娠结局关系的研究进展
糜小扬, 丁莹, 陈奕静, 贾洁

Research progress in the relationship between ultra-processed food intake and pregnancy outcomes
MI Xiaoyang, DING Ying, CHEN Yijing, JIA Jie
表1 UPFs摄入对妊娠结局的影响
Tab 1 Effect of intake of UPFs on gestational outcomes
Author

Year

Country

Study

design

Outcome

Number

(Case)

Dietary

Investigation

tool

UPF

consumption

OR

(95%CI or P value)

Covariate
MARTIN[23]

2015

USA

CohortPreterm birth3 143 (364)FFQ

Western

dietary

pattern

maximum

vs

minimum

OR=1.53

(1.02, 2.30)

Maternal age, race, pre-pregnancy BMI, educational level, marital status, parity, family income, smoking status in the first 6 months of pregnancy and energy intake
ENGLUND-ÖGGE[24]

2014

Norway

CohortPreterm birth66 000 (3 505)FFQ

Western

dietary

pattern

HR=1.12

(1.01, 1.25)

P>0.05

Maternal history of previous preterm delivery, maternal age, height, pre-pregnancy BMI, marital status, parity, smoking, education level, family income, and total energy intake
ENGLUND-ÖGGE[25]

2012

Norway

CohortPreterm birth

60 761

(3 281)

MoBa

FFQ

Sugar

-sweetened beverages

maximum

vs

minimum

Artificially sweetened

maximum

vs

minimum

OR=1.11

(1.00, 1.24)

OR=1.25

(1.08, 1.45)

Maternal history of previous preterm delivery, maternal age, pre-pregnancy BMI, marital status, parity, smoking, education level and total energy intake
RODRIGUES[26]

2020

Brazil

Cross

-sectional

LBW

99

(13)

Form of food consumption markers in the food and nutrition surveillance system

maximum

vs

minimum

OR=1.46

(1.02, 2.10)

Maternal age, marital status, education level, per capita income, prenatal weight, final fetal weight, increase in gestational age and gestational age, type of delivery, number of pregnancies
FERREIRA[27]

2022

Brazil

Cross

-sectional

LBW

260

(8)

FFQ

Dietary pattern 3

(rich in ultra-processed foods)

OR=1.27

(1.11, 1.45)

Maternal age, pre-pregnancy BMI, education level, marital status, family income and parity
VIEIRA E SOUZA[28]

2022

Brazil

Cross

-sectional

LBW

626

(43)

FFQ

maximum

vs

minimum

OR=1.72

(1.09, 2.70)

Maternal age, pre-pregnancy BMI, education level, percapita income, marital status, gestational weight gain, parity, number of prenatal consultations, smoking and physical activity level
SCHRUBBE[29]

2024

Brazil

CohortLGA

214

(22)

24hDietary Rcall

maximum

vs

minimum

OR=1.03

(1.00, 1.06)

Maternal age, pre-pregnancy BMI, race, education level, family income, marital status, parity, smoking and alcohol consumption
ROCHA[30]

2022

Brazil

Cross

-sectional

SGA

300

(17)

FFQ

UPF energy proportion>2.06%

vs

<0.31%

OR=10.4

(1.33, 8090)

Maternal age, pre-pregnancy BMI, total energy intake, education level, family income, marital status, parity, smoking, alcohol consumption and race
VICTOR[31]

2023

Brazil

Cross

-sectional

SGA

LBW

2 632 314

(186 206/188 450)

/

maximum

vs

minimum

OR=1.04

(1.02, 1.06)

OR=1.13

(1.11, 1.16)

Maternal age, marital status, education level, gestational age, number of prenatal appointments, newborn gender and race
LEONE[32]

2021

Spain

CohortGDM

3 730

(186)

FFQ

<3 servings/d

vs

>4.5servings/d

OR=1.10

P=0.82

Maternal age, pre-pregnancy BMI, education level, smoking, physical activity, family history of diabetes, parity, time spent watching TV, hypertension, nutritional therapy and total energy intake
LAMYIAN[33]

2017

Iran

CohortGDM

1 026

(71)

FFQ

maximum

vs

minimum

OR=2.12

(1.12, 5.43)

Maternal age, pre-pregnancy BMI, physical activity, family history of diabetes, history of GDM, smoking, drug use and total energy intake
YISAHAK[34]

2022

USA

Cohort

GDM

PE

1 948

(85/63)

FFQ

maximum

vs

minimum

OR=0.68

(0.44, 1.05)

OR=0.99

P=0.85

OR=1.33

P=0.63

Maternal age, pre-pregnancy BMI, race, family income, education level, marital status, parity, physical activity, sleep duration and total energy intake
SEDAGHAT[14]

2017

Iran

Case -controlGDM

388

(122)

FFQ

Western

dietary

pattern

OR=1.68

(1.04, 2.27)

Maternal age, pre-pregnancy BMI, gestational age, education level, socioeconomic status, smoking, family history of diabetes and supplement use
ASADI[35]

2019

Iran

Case -controlGDM

278

(130)

FFQ

Western

dietary

pattern

OR=1.50

(0.74, 3.03)

P=0.2

Maternal age, physical activity level, family history of diabetes, pre-pregnancy BMI, education level, occupational status, history of fetal macrosomia and total energy intake
DONAZAR-EZCURRA[36]

2018

Spain

CohortGDM

3 396

(172)

FFQSoft drink intake > 400 g/w

OR=2.03

(1.25, 3.31)

Maternal age, pre-pregnancy BMI, family history of diabetes, smoking, total energy intake, physical activity, parity, fast food intake, adherence to Mediterranean dietary patterns, alcohol intake, multiple pregnancies and cardiovascular disease/hypertension
BRANTSAETER[15]

2009

Norway

CohortPE

23 423

(1 267)

FFQ

Western

dietary

pattern

OR=1.21

(1.03, 1.42)

Maternal age, pre-pregnancy BMI, education level, smoking, pre-pregnancy hypertension status, dietary supplement use and total energy intake
IKEM[37]

2019

Danmark

Cohort

Gestationalhypertension

PE

55 139

(5 491)

FFQ

Western

dietary

pattern

Gestational

hypertension

OR=1.18

(1.05, 1.33)

PE OR=1.40

(1.11, 1.76)

Maternal age, pre-pregnancy BMI, parity, smoking, physical activity level, paired sociodemographic status, total energy intake and previous history of hypertension