芦丁对骨肉瘤生长和转移的体内外抑制作用

李想, 魏鸣, 吴文曦, 罗小琴, 姚彪, 伍思宇

Inhibitory effect of rutin on the growth and metastasis of osteosarcoma in vitro and in vivo

LI Xiang, WEI Ming, WU Wenxi, LUO Xiaoqin, YAO Biao, WU Siyu

图3 芦丁对骨肉瘤细胞凋亡的影响 Note： A. Apoptosis was detected by flow cytometry and the apoptosis rate of MG63 cells was analyzed. B. Apoptosis was detected by flow cytometry and the apoptosis rate of MG63 and U2OS cells was analyzed. C. The expression of Bax and Bcl-2 proteins was detected by Western blotting and the Bax/Bcl-2 ratio in MG63 and U2OS cells was calculated. ①P=0.001, ②P<0.001, compared with the rutin 0 μmol/L group.

Fig 3 Effect of rutin on the apoptosis of osteosarcoma cells