LINC01123通过结合ENO1促进胃癌的增殖和糖酵解

张舒琼, 柯星, 赵兴贺, 陈晓翠, 郑浩东, 陈惠, 沈立松, 杨俊瑶

LINC01123 promotes proliferation and glycolysis of gastric cancer via binding to ENO1

ZHANG Shuqiong, KE Xing, ZHAO Xinghe, CHEN Xiaocui, ZHENG Haodong, CHEN Hui, SHEN Lisong, YANG Junyao

图4 LINC01123对EMT及PI3K/AKT信号通路的调控作用 Note：A. Volcano plot of differentially expressed lncRNAs. B. KEGG enrichment results of differentially expressed genes in MKN-45 cells transfected with si-NC and si-LINC01123. C. GO enrichment results of differentially expressed genes in MKN-45 cells transfected with si-NC and si-LINC01123. D. Heatmap of genes defining epithelial-mesenchymal transition (EMT). E. Heatmap of genes up-regulated by activation of the PI3K/AKT/mTOR pathway.

Fig 4 Regulatory role of LINC01123 in EMT and PI3K/AKT pathway