CD10+中性粒细胞通过SELPLG-SELL通路促进黏膜恶性黑色素瘤CD8+ T细胞耗竭

郝美灵, 马彦妮, 马旭辉, 张燕捷, 曾汉林, 陈善双

CD10+ neutrophils promote CD8+ T-cell depletion in mucosal malignant melanoma through the SELPG-SELL pathway

HAO Meiling, MA Yanni, MA Xuhui, ZHANG Yanjie, ZENG Hanlin, CHEN Shanshuang

图3 黏膜与皮肤恶性黑色素瘤微环境中中性粒细胞亚群的特征差异 Note： A. UMAP of neutrophil clustering between mucosal and skin melanism. B. Proportion distribution of neutrophil types. C. Analysis of the enrichment of GO and KEGG genes in different subpopulations of neutrophils.

Fig 3 Differences in the characteristics of neutrophil subpopulations in the microenvironment of mucosal and cutaneous malignant melanoma