ABCA7在结直肠癌中的临床价值及转录调控机制

孙瑞状, 乔坤朋, 李璞, 徐小莲, 孟俊

Clinical value and transcriptional regulatory mechanism of ABCA7 in colorectal cancer

SUN Ruizhuang, QIAO Kunpeng, LI Pu, XU Xiaolian, MENG Jun

图7 ABCA7 对 CRC 中高表达 ZBTB33 和 NKRF 的表观遗传调控及基因网络解析 Note： Integration of multi-omics data (chromatin accessibility, gene expression, epigenetic regulatory elements, etc.) to present the epigenetic regulatory effect of ABCA7 on highly expressed ZBTB33 and NKRF in CRC, and analysis of CRC gene regulatory network through chromatin status and binding element regulation.

Fig 7 Epigenetic regulation of ABCA7 on highly expressed ZBTB33 and NKRF in CRC and analysis of gene network