二氧化氮短期暴露对上海市老年人血管内皮功能的影响

钟林杉, 丁琳, 姜绮霞

Impact of short-term exposure to nitrogen dioxide on vascular endothelial function in elderly residents of Shanghai

ZHONG Linshan, DING Lin, JIANG Qixia

表2 FMD百分比变化与VED风险分析

Tab 2 Percentage change in FMD and risk of VED for every IQR increase in NO2 concentration （95%CI）

Item Model 1 P value Model 2 P value Model 3 P value FMD Lag0/% -18.00 (-32.56, -3.44) 0.015 -20.99 (-38.71, -3.27) 0.020 -21.40 (-39.13, -3.67) 0.018 Lag1/% -19.49 (-34.03, -4.95) 0.009 -26.40 (-43.83, -8.96) 0.003 -26.87 (-44.34, -9.40) 0.003 Lag2/% -14.86 (-29.48, -0.24) 0.046 -18.78 (-36.85, -0.71) 0.042 -19.53 (-37.62, -1.44) 0.034 Lag3/% -12.30 (-26.99, 2.39) 0.101 -17.20 (-35.56, 1.16) 0.066 -18.14 (-36.52, 0.24) 0.053 Lag4/% -8.86 (-23.81, 6.08) 0.245 -14.18 (-32.17, 3.81) 0.122 -15.05 (-33.10, 3.00) 0.102 Lag5/% -15.87 (-30.63, -1.12) 0.035 -18.49 (-35.28, -1.69) 0.031 -19.64 (-36.48, -2.81) 0.022 Lag6/% -12.94 (-27.78, 1.90) 0.087 -14.82 (-32.36, 2.72) 0.098 -15.93 (-33.49, 1.63) 0.075 Lag7/% -9.43 (-24.09, 5.24) 0.208 -10.54 (-27.70, 6.62) 0.229 -11.96 (-29.14, 5.23) 0.173 Lag8/% -11.50 (-26.28, 3.27) 0.127 -12.08 (-28.82, 4.66) 0.157 -13.48 (-30.21, 3.25) 0.114 Lag9/% -8.13 (-22.77, 6.50) 0.276 -6.73 (-23.45, 9.99) 0.430 -8.07 (-24.82, 8.67) 0.345 Lag10/% -6.19 (-20.77, 8.39) 0.405 -6.53 (-23.36, 10.30) 0.447 -7.55 (-24.44, 9.34) 0.381 VED Lag0 1.21 (1.04, 1.41) 0.014 1.26 (1.04, 1.53) 0.019 1.27 (1.05, 1.55) 0.016 Lag1 1.13 (0.97, 1.31) 0.111 1.17 (0.97, 1.42) 0.106 1.18 (0.98, 1.44) 0.092 Lag2 1.11 (0.96, 1.29) 0.166 1.14 (0.94, 1.39) 0.189 1.15 (0.94, 1.40) 0.169 Lag3 1.12 (0.97, 1.31) 0.139 1.17 (0.96, 1.43) 0.122 1.18 (0.97, 1.45) 0.107 Lag4 1.06 (0.91, 1.23) 0.448 1.10 (0.90, 1.33) 0.339 1.11 (0.91, 1.35) 0.300 Lag5 1.20 (1.03, 1.40) 0.020 1.26 (1.04, 1.51) 0.015 1.27 (1.05, 1.53) 0.013 Lag6 1.16 (0.99, 1.35) 0.061 1.20 (0.99, 1.46) 0.066 1.22 (1.01, 1.49) 0.045 Lag7 1.04 (0.90, 1.21) 0.603 1.03 (0.85, 1.24) 0.759 1.04 (0.86, 1.26) 0.687 Lag8 1.14 (0.98, 1.33) 0.093 1.18 (0.98, 1.41) 0.075 1.19 (0.99, 1.43) 0.064 Lag9 1.07 (0.92, 1.24) 0.374 1.05 (0.88, 1.26) 0.594 1.06 (0.88, 1.27) 0.534 Lag10 1.03 (0.88, 1.19) 0.701 1.02 (0.85, 1.22) 0.830 1.03 (0.85, 1.24) 0.759