人胚胎干细胞向神经前体细胞分化的转录组与染色质可及性变化分析研究

李林颖, 蔡晓东, 童冉, 杨晨, 王志明, 贺潇宇, 马子越, 张丰, 李令杰, 周君梅

Analysis of transcriptome and chromatin accessibility changes during the differentiation of human embryonic stem cells into neural progenitor cells

LI Linying, CAI Xiaodong, TONG Ran, YANG Chen, WANG Zhiming, HE Xiaoyu, MA Ziyue, ZHANG Feng, LI Lingjie, ZHOU Junmei

图6 PPI网络分析揭示下游候选中心基因 Note： The thickness of the edge in the network diagram represents the interaction strength between the two proteins, and the size of the node represents the degree. The red circles represent the protein with degree≥10, and the others represent proteins that interact with the red proteins.

Fig 6 Candidate hub downstream genes detected by PPI network analysis