人胚胎干细胞向神经前体细胞分化的转录组与染色质可及性变化分析研究

李林颖, 蔡晓东, 童冉, 杨晨, 王志明, 贺潇宇, 马子越, 张丰, 李令杰, 周君梅

Analysis of transcriptome and chromatin accessibility changes during the differentiation of human embryonic stem cells into neural progenitor cells

LI Linying, CAI Xiaodong, TONG Ran, YANG Chen, WANG Zhiming, HE Xiaoyu, MA Ziyue, ZHANG Feng, LI Lingjie, ZHOU Junmei

表4 对在NPC差异上调的开放染色质信号进行基序富集分析

Tab 4 Motif enrichment analysis of open chromatin signals that were differentially upregulated at the NPC stage

Motif E value Motif ID Motif E value Motif ID 2.38×10-111 DLX1 1.05×10-100 NKX6.1 6.26×10-109 SHOX 2.79×10-91 LHX2 6.18×10-101 MSX1