利拉鲁肽改善非酒精性脂肪性肝病小鼠肝纤维化的作用及其机制

王仁杰, 祝超瑜, 方云云, 肖元元, 王倩倩, 宋雯婧, 魏丽

Effects and mechanisms of liraglutide in ameliorating liver fibrosis in NAFLD mice

WANG Renjie, ZHU Chaoyu, FANG Yunyun, XIAO Yuanyuan, WANG Qianqian, SONG Wenjing, WEI Li

图1 利拉鲁肽对小鼠体质量与肝功能的影响 Note： A. Representative pictures of mice in each group. B. Body weight changes after 6 weeks. C/D. ALT (C) and AST (D) levels treated with liraglutide after 4 weeks. ①P=0.043, compared with the Chow＋LG group; ②P<0.001, compared with the MCD＋Saline group. LG—liraglutide.

Fig 1 Effect of liraglutide on body weight and liver function in mice