利拉鲁肽改善非酒精性脂肪性肝病小鼠肝纤维化的作用及其机制

王仁杰, 祝超瑜, 方云云, 肖元元, 王倩倩, 宋雯婧, 魏丽

Effects and mechanisms of liraglutide in ameliorating liver fibrosis in NAFLD mice

WANG Renjie, ZHU Chaoyu, FANG Yunyun, XIAO Yuanyuan, WANG Qianqian, SONG Wenjing, WEI Li

图5 利拉鲁肽对小鼠肝纤维化蛋白表达的影响 Note： A. Expression of FN, COL1A, α-SMA, MMP9, TIMP1, and HSP90 proteins detected by Western blotting. B－F. The relative expression levels of COL1A (B), α-SMA (C), FN (D), MMP9(E), and TIMP1 (F) proteins in the liver of mice.

Fig 5 Effect of liraglutide on indices of liver fibrosis protein in mice