经颅磁刺激治疗对抑郁症患者杏仁核及海马亚区体积的影响

王思睿, 孔盖, 李惠, 钱禛颖, 崔慧茹, 唐莺莹

Impact of transcranial magnetic stimulation therapy on the volumes of amygdala and hippocampal subfields in patients with major depressive disorder

WANG Sirui, KONG Gai, LI Hui, QIAN Zhenying, CUI Huiru, TANG Yingying

表3 TMS干预前后双侧海马亚区体积双因素方差分析

Tab 3 Two-way ANOVA of bilateral hippocampal subfield volumes before and after TMS treatment

Subfield Time Laterality Time × Laterality F value P value η2 F value P value η2 F value P value η2 CA1-body 3.910 0.053 0.064 67.705 <0.001 0.543 4.673 0.035 0.067 CA1-head 0.148 0.702 0.003 86.886 <0.001 0.604 1.217 0.275 0.021 CA3-body 12.769 <0.001 0.183 82.281 <0.001 0.591 7.449 0.008 0.166 CA3-head 0.261 0.611 0.005 21.449 <0.001 0.273 1.851 0.179 0.031 CA4-body 6.293 0.015 0.099 1.844 0.180 0.031 0.002 0.968 <0.001 CA4-head 0.026 0.872 0.0005 20.487 <0.001 0.264 3.107 0.083 0.052 Fimbria 15.254 <0.001 0.211 7.824 0.007 0.121 1.837 0.181 0.031 Fissure 0.874 0.354 0.015 1.970 0.166 0.033 0.247 0.621 0.004 GC-DG-body 6.720 0.012 0.105 1.966 0.166 0.033 0.125 0.725 0.002 GC-DG-head 0.001 0.973 <0.001 25.200 <0.001 0.307 2.654 0.109 0.044 HATA 0.370 0.546 0.006 6.398 0.014 0.101 0.684 0.412 0.012 Hippocampus tail 26.765 <0.001 0.320 65.029 <0.001 0.533 0.267 0.608 0.005 ML-body 20.469 <0.001 0.264 44.278 <0.001 0.437 7.873 0.007 0.121 ML-head 0.007 0.936 <0.001 34.724 <0.001 0.379 2.142 0.149 0.036 Parasubiculum 0.064 0.801 0.001 13.377 <0.001 0.190 0.279 0.599 0.005 Presubiculum-body 6.277 0.015 0.099 18.069 <0.001 0.241 1.514 0.224 0.026 Presubiculum-head 3.017 0.083 0.052 15.834 <0.001 0.217 0.637 0.428 0.011 SUB-body 17.011 <0.001 0.230 0.010 0.921 <0.001 1.019 0.317 0.018 SUB-head 0.278 0.600 0.005 1.118 0.295 0.019 0.166 0.685 0.003 Whole hippocampus 10.728 0.002 0.158 65.042 <0.001 0.533 2.941 0.092 0.049 Whole hippocampus-body 14.750 <0.001 0.206 12.169 <0.001 0.176 3.168 0.080 0.053 Whole hippocampus-head 0.034 0.855 0.001 33.231 <0.001 0.368 1.459 0.232 0.025