基于单细胞测序与转录组测序构建M2巨噬细胞基因相关的前列腺癌预后模型
Integrated single-cell and transcriptome sequencing to construct a prognostic model of M2 macrophage-related genes in prostate cancer
Note： A. The comparison of PFS between low- and high-risk score groups in the test set. B. The prediction accuracy of the risk score measured by ROC curves at 1, 3, 5 years in the test set. The AUC values were 0.693, 0.659, and 0.649 for 1, 3, and 5 years, respectively. C. Distribution of risk in ascending order and comparison of survival status between low- and high- risk score groups in the test set. D. The heatmap of four signature genes between high- and low-risk group. E/F. The comparison of BCR (E) and OS (F) between low- and high-risk score groups in the SU2C/PCF Dream Team cohort. G. Nomogram for predicting PFS of patients in training set. H. The calibration plots of the nomogram at 1, 3, 5 years. The x coordinate value represents the nomogram-predicted survival, and the y coordinate value represents observed PFS. I. ROC curves for nomogram at 1, 3, 5 years. ①P=0.018, ②P<0.001, ③P=0.013.
