维生素D联合DHA补充干预学龄前注意缺陷多动障碍的疗效研究
张玥, 张丽珊, 丁肖媛, 沈植旻, 卞邹吉, 余晓丹

Therapeutic effect of combined vitamin D and DHA supplementation on preschool children with attention deficit hyperactivity disorder
ZHANG Yue, ZHANG Lishan, DING Xiaoyuan, SHEN Zhimin, BIAN Zouji, YU Xiaodan
表1 2组患儿干预前一般情况及血清25OHDDHA水平比较
Tab 1 Comparison of baseline characteristics and serum 25(OH)D and DHA levels between the two groups
ItemTotal (n=82)Nutrition intervention group (n=64)Control group (n=18)t /χ2 valueP value
Gender/n (%)0.460.527
Male64 (78.05)51 (79.69)13 (72.22)
Female18 (21.95)13 (20.31)5 (27.78)
Age/year5.23±0.815.25±0.755.17±0.960.300.768
IQ/score119.56±13.80120.81±14.87116.75±11.100.850.403
Maternal age/year33.00±3.3333.05±3.4732.93±3.260.100.920
Paternal age/year34.29±3.7634.60±3.2633.87±3.720.570.576
Maternal education level/n (%)1.290.525
High school degree9 (10.98)6 (9.38)3 (16.67)
College degree45 (54.88)37 (57.81)8 (44.44)
Bachelor degree or above28 (34.14)21 (32.81)7 (38.89)
Paternal education level/n (%)0.510.776
High school degree5 (6.10)4 (6.25)1 (5.56)
College degree42 (51.22)34 (53.13)8 (44.44)
Bachelor degree or above35 (42.68)26 (40.62)9 (50.00)
Annual household income/n (%)1.060.588
<300 000 yuan10 (12.19)9 (14.06)1 (5.56)
300 000‒500 000 yuan65 (79.27)50 (78.13)15 (83.33)
>500 000 yuan7 (8.54)5 (7.81)2 (11.11)
25(OH)D/(ng·mL-1)26.73±4.9324.42±3.4627.97±5.88-0.160.874
Vitamin D status/n (%)0.500.779
Deficiency6 (7.32)4 (6.25)2 (11.11)
Insufficient53 (64.63)42 (65.63)11 (61.11)
Sufficient23 (28.05)18 (28.12)5 (27.78)
DHA/(nmol·mL-1)159.83±45.89156.54±42.37173.47±85.64-1.620.114