两样本孟德尔随机化分析血浆磷脂酰乙醇胺水平与结直肠腺癌发病风险的关系

徐苓, 皇甫昱婵, 沈立松, 马妍慧

Causal association between plasma phosphatidylethanolamine and risk of colorectal adenocarcinoma: a two-sample Mendelian randomization study

XU Ling, HUANGFU Yuchan, SHEN Lisong, MA Yanhui

图1 PE相关SNP与结直肠腺癌风险关联的森林图 Note： The black dots represent the log ORs for colorectal adenocarcinoma using each PE-associated SNP as an instrumental variable, corresponding to the risk per one standard deviation increase in PE levels. The red dots represent the combined causal estimates, derived using all SNPs as instrumental variables, based on the MR-Egger regression and IVW methods. The horizontal lines represent the 95%CI of the estimates.

Fig 1 Forest plot of the association of PE-associated SNPs with risk of colorectal adenocarcinoma