白介素-1β在极重症口腔颌面部感染中的预警价值及机制初探

朱晗懿, 石欢, 俞创奇, 郑凌艳

Preliminary study on early warning value and mechanism of interleukin-1β in extremely severe oral and maxillofacial space infections

ZHU Hanyi, SHI Huan, YU Chuangqi, ZHENG Lingyan

图2 OMSI患者与健康对照者的PBMCs的单细胞转录组图谱 Note： A. An overview of the study design and workflow. B. UMAP plot showing integrated analysis of 8 samples. C. UMAP plot showing clustering of 4 immune cell subtypes in 8 samples. D. Heatmap showing the expression of the top 5 genes in each cluster. E. Bar plot showing the ratio of each cell subtype in 4 groups. B—B cell; Mono—monocyte; DC—dendritic cell. F. Feature plot showing the expression of IL1B in each cell subtype. G. Expression of NLRP3, IL1B, TLR2, NFKB1, CASP8, CAT, PRDX3, ATG7 and ULK1 among 4 groups in violin plot.

Fig 2 Single-cell transcriptomic atlas of PBMCs from OMSI patients and healthy controls