白介素-1β在极重症口腔颌面部感染中的预警价值及机制初探

朱晗懿, 石欢, 俞创奇, 郑凌艳

Preliminary study on early warning value and mechanism of interleukin-1β in extremely severe oral and maxillofacial space infections

ZHU Hanyi, SHI Huan, YU Chuangqi, ZHENG Lingyan

图4 OMSI患者与健康对照者PBMCs单细胞转录组二级聚类 Note： A. UMAP plot showing clustering into 11 immune cell subtypes. B. Bar plot showing the ratio of each cell subtype in 4 groups. C. Dotplot showing cluster-defining gene expression across the 11 immune cell subtypes. D. Expression of NLRP3, CASP1, PYCARD and IL1B in monocyte subtypes. B—B cell; mDC—myeloid dendritic cell; pDC—plasmacytoid dendritic cell.

Fig 4 Secondary clustering of single-cell transcriptomic profiles of PBMCs from OMSI patients and healthy controls