亚精胺对脂多糖诱导的小鼠颅骨炎症性骨溶解的作用研究

赵心雨, 张文超, 陈旭卓, 宋佳琪, 黄慧, 张善勇

Study on the effects of spermidine on LPS-induced inflammatory osteolysis in mouse calvaria

ZHAO Xinyu, ZHANG Wenchao, CHEN Xuzhuo, SONG Jiaqi, HUANG Hui, ZHANG Shanyong

图3 SPD对LPS激活的巨噬细胞促炎基因表达的影响 Note： A‒C. mRNA levels of Nos2 (A), Tnf (B), and Il6 (C). ①P<0.001, compared with the control group; ②P=0.031, ③P=0.001, ④P<0.001, compared with the LPS group.

Fig 3 Effects of SPD on expression levels of pro-inflammatory genes in LPS-activated macrophages