亚精胺对脂多糖诱导的小鼠颅骨炎症性骨溶解的作用研究

赵心雨, 张文超, 陈旭卓, 宋佳琪, 黄慧, 张善勇

Study on the effects of spermidine on LPS-induced inflammatory osteolysis in mouse calvaria

ZHAO Xinyu, ZHANG Wenchao, CHEN Xuzhuo, SONG Jiaqi, HUANG Hui, ZHANG Shanyong

图4 SPD对RANKL诱导的破骨细胞分化的影响 Note： A. TRAP staining of mouse BMMs 5 d after RANKL stimulation (×200). B. Number of positive cells.C. Percentage of positive cell area. ①P=0.002, ④P<0.001, compared with the control group; ②P=0.041, ③P=0.003, ⑤P=0.001, ⑥P<0.001, compared with the RANKL group.

Fig 4 Effects of SPD on RANKL-induced osteoclast differentiation