HENMT1通过激活PI3K-AKT-mTOR信号通路促进胃癌的增殖与迁移

杨娜, 刘俊丽, 白静, 杨思怡, 韩继明, 张华华

HENMT1 promotes the proliferation and migration of gastric cancer by activating the PI3K-AKT-mTOR signaling pathway

YANG Na, LIU Junli, BAI Jing, YANG Siyi, HAN Jiming, ZHANG Huahua

图4 HENMT1 促进胃癌细胞的增殖和迁移 Note： A. The efficacy of the HENMT1 overexpression plasmid was assessed through Western blotting. B/C. CCK-8 assay and clone formation assay were utilized to assess the HENMT1 effects on cell proliferation in gastric cancer cells. D/E. The influence of HENMT1 on cell migration was investigated using cell scratch and Transwell assays. F. Changes in migration-related proteins were identified via Western blotting. ①P=0.002, ②P=0.003, compared with the Vector group.

Fig 4 HENMT1 promotes proliferation and migration of gastric cancer cells