孟德尔随机化分析乳糜泻与自身免疫性甲状腺疾病的因果关系

闫军浩, 郭晓磊, 罗昭锋, 唐坚, 王争

Mendelian randomization analysis of causal relationship between celiac disease and autoimmune thyroid disease

YAN Junhao, GUO Xiaolei, LUO Zhaofeng, TANG Jian, WANG Zheng

Exposure-Outcome Method Heterogeneity Pleiotropy Cochran's Q P value Intercept SE P value ebi-a-GCST005523-HT MR Egger 20.95 0.890 <0.001 0.02 0.930 IVW 20.96 0.910 GCST90436342-HT MR Egger 9.81 0.130 0.020 0.08 0.790 IVW 9.94 0.190 ebi-a-GCST005523-GD MR Egger 16.70 0.610 -0.010 0.01 0.620 IVW 16.95 0.660 GCST90436342-GD MR Egger 5.03 0.410 0.020 0.03 0.600 IVW 5.34 0.500 GD-ebi-a-GCST005523 MR Egger 10.95 <0.001 -0.020 0.09 0.840 IVW 11.23 0.010 GD-GCST90436342 MR Egger 9.54 0.480 0.010 0.04 0.780 IVW 9.62 0.560