金丝桃素通过抑制NF-κB信号通路减轻糖尿病肾病足细胞损伤

韩珍, 王浩, 苏秀秀, 方际

Hypericin alleviates podocyte injury in diabetic nephropathy by inhibiting the NF-κB signaling pathway

Han Zhen, Wang Hao, Su Xiuxiu, Fang Ji

图1 金丝桃素在 db/db 小鼠肾脏和HPCs中的分布 Note： Fluorescence intensity in the organs of db/db mice at 4 h after intravenous injection of HYP (5 mg/kg). A. In vivo imaging showed fluorescence intensity. B. Line graph of background-subtracted fluorescence intensity in various organs. ①P=0.021, compared with the heart. C. Fluorescence intensity of HYP in HPCs at different time points (×200). Scale bar=20 μm.

Fig 1 Distribution of HYP in the kidneys of db/db mice and HPCs