金丝桃素通过抑制NF-κB信号通路减轻糖尿病肾病足细胞损伤

韩珍, 王浩, 苏秀秀, 方际

Hypericin alleviates podocyte injury in diabetic nephropathy by inhibiting the NF-κB signaling pathway

Han Zhen, Wang Hao, Su Xiuxiu, Fang Ji

图3 HYP干预对 db/db 小鼠糖脂代谢的影响 Note： HYP reduced insulin levels and ameliorated glucose and lipid metabolic disorders in db/db mice. A. Insulin levels. B. Fasting blood glucose levels. C. Total cholesterol (TC). D. Triglycerides (TAG). E. Low-density lipoprotein (LDL). F. High-density lipoprotein (HDL). ①P<0.001, compared with the db/m group; ②P=0.003,③P=0.027, ④P=0.032,⑤P=0.006,⑥P=0.017,⑦P=0.002, compared with the model group (n=6).

Fig 3 Effect of HYP intervention on glucose and lipid metabolism in db/db mice