金丝桃素通过抑制NF-κB信号通路减轻糖尿病肾病足细胞损伤

韩珍, 王浩, 苏秀秀, 方际

Hypericin alleviates podocyte injury in diabetic nephropathy by inhibiting the NF-κB signaling pathway

Han Zhen, Wang Hao, Su Xiuxiu, Fang Ji

图7 HYP下调炎症因子表达 Note：Inflammatory cytokine levels across groups. A.TNF-α (pg/mL), IL-1β (pg/mL), IL-6 (pg/mL), and MCP-1(ng/mL). ①P<0.001, compared with the db/m group; ②P<0.001, compared with the model group (n=6). B. The mRNA expression levels of TNF-α, IL-1β, IL-6, and MCP-1. ③P<0.001, compared with the NG group; ④P<0.001, compared with the HG group.

Fig 7 HYP downregulates the expression of inflammatory cytokines