去泛素化酶USP38通过稳定RBM14促进胃癌进展的机制研究

陈赟琪, 那迪娜·帕尔哈提, 张鹏善, 黄陈

Deubiquitinase USP38 promotes gastric cancer progression by stabilizing RBM14

Chen Yunqi, Paerhati Nadina, Zhang Pengshan, Huang Chen

图2 USP38促进胃癌细胞增殖和迁移的作用 Note： A. Validation of USP38 knockdown efficiency in AGS and HGC-27 gastric cancer cells by qPCR. B‒D. CCK-8 assay (B), colony formation assay (C), and EdU assay (D) assessing the effect of USP38 knockdown on the proliferation of AGS and HGC-27 gastric cancer cells. E. Wound healing assay examining the effect of USP38 knockdown on the migration of AGS and HGC-27 gastric cancer cells. Data are presented as mean±SD (unpaired t‑test, shUSP38vs shNC).

Fig 2 Promotive effects of USP38 on proliferation and migration of gastric cancer cells