上海交通大学学报（医学版）

›› 2010, Vol. 30 ›› Issue (2): 236-.

• 综述 • 上一篇    下一篇

胃癌癌前病变相关研究进展

张叶丽, 综述；胡梅洁, 审校   

  1. 上海交通大学 医学院瑞金医院消化内科, 上海 200025
  • 出版日期:2010-02-25 发布日期:2010-02-25
  • 通讯作者: 胡梅洁, 电子信箱: humeijie@medmail.com.cn。
  • 作者简介:张叶丽（1984—）, 女, 硕士生；电子信箱: marria_saint@hotmail.com。

Research advances in precancerous lesions of stomach

ZHANG Ye-li, reviewer；HU Mei-jie, reviser   

  1. Department of Gastroenterology, Ruijin Hospital,School of Medicine, Shanghai Jiaotong University, Shanghai 200025, China
  • Online:2010-02-25 Published:2010-02-25

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摘要：

胃癌癌前病变是指胃黏膜上皮异型增生（不典型增生或上皮内瘤变），具有恶变倾向，与胃癌的发生关系密切且受多种因素影响和调控。在胃癌癌前病变的形成过程中，饮食和环境因素以及幽门螺杆菌感染占有重要位置。近年来，相关学者对胃癌癌前病变的发生及其癌变机制进行了深入研究，文章就该方面的研究进展作一综述。

关键词: 胃癌, 癌前病变, 幽门螺杆菌, 异型增生

Abstract:

Gastric precancerous lesion refers to epithelial dysplasia (atypical hyperplasia or intraepithelial neoplasias), which is associated with increased risk of gastric cancer. It happens to be controlled by multiple factors and/or polygene such as the H. pylori infection, diet and environment which play an important role in the development of gastric precancerous lesions. This article describes the pathogenesis of gastric precancerous lesions as many scholars have studied some of it.

Key words: gastric cancer, precancerous lesions, helicobacter pylori, epithelial dysplasia