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Clinical application of PET/CT in staging and restaging of Wilms' tumor

TANG Yi-yun1, WANG Hui1, QIN Zhen2, FU Hong-liang1, LI Jia-ning1, MA Chao1, ZOU Ren-jian1   

  1. 1.Department of Nuclear Medicine, 2.Department of Pediatric Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200092, China
  • Online:2013-10-28 Published:2013-10-31

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Abstract:

Objective To investigate the clinical application of 18F-fluorodeoxyglucose positron emission tomography with computerized tomography (18F-FDG-PET/CT) in staging and restaging of Wilms' tumor. Methods The imaging data of 18F-FDG-PET/CT of 26 children with Wilms' tumor were retrospectively analysed, and the specificity, sensitivity, positive predictive value, negative predictive value and accuracy of PET/CT in staging of Wilms' tumor were calculated. Results The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of PET/CT in staging of Wilms' tumor were 94.6%, 70.7%, 85.4%, 87.9%, and 86.1%, respectively. Conclusion 18F-FDG-PET/CT has definite value in staging and restaging of Wilms tumor.

Key words: Wilms' tumor, neoplasm staging, 18F-FDG-PET/CT