›› 2017, Vol. 37 ›› Issue (6): 758-.doi: 10.3969/j.issn.1674-8115.2017.06.008

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Clinical analysis of mandibular reconstructions using synthetic bones based on three-dimensional printing technology in 149 cases

ZIN Mar Aung*, HAN Wen-qing*, CHEN Xiao-jun, LIN Li, ZHANG Yan, XU Hai-song, CHAI Gang   

  1. Department of Plastic and Reconstructive Surgery, Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200011, China
  • Online:2017-06-28 Published:2017-07-05
  • Supported by:

    National Natural Science Foundation of China, 81372097; Project of Science and Technology Commission of Shanghai Municipality, 14441900800, 14441900802; Research Fund of Shanghai Jiao Tong University, YG2014MS06; Shanghai Municipal Education Commission—Gaofeng Clinical Medicine Grant Support, 20161420


Objective · To assess the clinical value of the computer-assisted three-dimensional reconstruction technique design and evaluate the clinical experience of manufacture artificial bone precision to repair the mandibular defect.  Methods · From 2001 to 2016, 163 computer-assisted reconstruction surgeries had been performed in Craniofacial Department, Ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine. During six months followup, the measurement data was conducted and compared with three-dimensional CT result. Random measurement of the three key anatomical points pre- and post-operative carried out with statistical error was used to evaluate the accuracy of computer-assisted three-dimensional reconstruction in mandibular defects repairation and to investigate the clinical application value of the operation time and postoperative complication rate.  Results · From July 2001 to July 2016, a total of 163 patients underwent computer-assisted three-dimensional reconstruction of artificial bone repair for mandibular defects; 149 patients met the statistical criteria in which preoperative design and postoperative actual effect’s average distance error (1.27±0.15) mm, operation time (2.5±1.2) h.  Conclusion · Threedimensional design of artificial bone to repair the mandibular defect is a valuable technology, by relying on quantitative design and preoperative simulation to simplify the difficulty and improve the accuracy of surgery. The patients showed high satisfaction rate with low surgical complications and long-term efficacy.

Key words:  computer-assisted surgery, mandibular reconstruction, synthetic bone, three dimensional printing