Abstract: Objective · To evaluate the clinical efficacy of laparoscopic-assisted Soave radical operation in the treatment of children with congenital megacolon. Methods · The clinical datum of 148 pediatric patients with congenital megacolon who had underwent laparoscopic-assisted Soave radical operation in Hainan General Hospital Mar. 2012 to Sept. 2015 were collected. Operation time, blood volume lost during the operation, complication incidence during the hospitalization and follow-up period were analyzed, retrospectively. Results · All 148 patients were finished the surgery successfully. Operation time was (121.66±22.98) min, blood volume lost during the operation was (4.86±0.66) mL. During the hospitalization, the incidence of complications was 8.10%. There were no short-term complications observed on abdominal bleeding and anastomotic leakage. The patients were followed up for 24 months, there was one patient with anastomotic stoma stenosis at the 6 months after the operation, who recovered after the treatment of anal dilation. All the pediatric patients′ stool were mushy within 3 months after the operation, and they recovered to normal at the 6-12 months. The excellent rate of defecation function was 97.97%. There were no symptoms of bloated abdomen and astriction for all the patients during the follow-up period. Conclusion · Laparoscopic-assisted Soave radical operation is effective and safe for the treatment of children with congenital megacolon, with few complications, quick recovery, good short-term and long-term clinical effect.

Key words: congenital megacolon, laparoscopy, Soave radicaloperation, clinical efficacy