JOURNAL OF SHANGHAI JIAOTONG UNIVERSITY (MEDICAL SCIENCE) ›› 2020, Vol. 40 ›› Issue (05): 646-650.doi: 10.3969/j.issn.1674-8115.2020.05.013

• Original article (Clinical research) • Previous Articles     Next Articles

Application of 18F-FDG PET/CT-guided percutaneous biopsy to differential diagnosis of peritoneal thickening diseases

WANG Hai-yan, YOU Zhi-wen, SHOU Yi, MENG Qing-yuan, CHEN Hui-qian, ZHAO Jun   

  1. Department of Nuclear Medicine, Shanghai East Hospital, Tongji University, Shanghai 200120, China
  • Online:2020-05-28 Published:2020-05-28
  • Supported by:
    Project of Science and Technology Commission of Shanghai Municipality (19DZ1930703); Key Specialty Construction Project of Pudong Health and Family Planning Commission of Shanghai (PWZzk2017-24).

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Abstract: Objective · To investigate the clinical value of 18F-flurodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) -guided percutaneous biopsy in peritoneal thickening of unknown origin. Methods · Ten cases of peritoneal thicken of unknown origin including 4 males and 6 females were analyzed. After 18F-FDG PET/CT examination, the peritoneal thickening regions with high 18F-FDG uptake were selected for the target areas. Percutaneous biopsy was operated under the guidance of the same PET/CT machine. Results · All lesions were successfully obtained by one-time puncture without serious complications, and histopathological diagnosis revealed that 7 cases were malignant, including 4 cases of peritoneal metastasis and 3 cases of lymphoma. The remaining cases were 1 case of pseudomyxoma, 1 case of tuberculosis and 1 case of inflammatory lesions. The accuracy of biopsy was 100%. Conclusion · 18F-FDG PET/CT-guided peritoneal percutaneous biopsy is a safe and effective method, and may play an important role in differential diagnosis and treatment management.

Key words: peritoneum, percutaneous biopsy, positron emission tomography/computed tomography (PET/CT), 18F-flurodeoxyglucose (18F-FDG)

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