›› 2011, Vol. 31 ›› Issue (9): 1347-.doi: 10.3969/j.issn.1674-8115.2011.09.032

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Effect of afterload pressure on hemolytic blood damage in Sarns2000 centrifugal pump

HAN Lu1,2, WANG Wei1,2, YU Xiao-qing1, DING Wen-xiang1   

  1. 1. Department of Cardiovascular and Thoracic Surgery, 2. Institute of Pediatric Translational Medicine, Shanghai Children's Medical Center, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China
  • Online:2011-09-28 Published:2011-09-27
  • Supported by:

    Foundation of Development and Innovation of Science and Technology of Pudong New Area, Shanghai, PKJ2010-Y30

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Abstract:

Objective To investigate the effect of afterload pressure on hemolytic blood damage in centrifugal pump. Methods The differences between velocity, pressure and surface shear force of the internal flow of Sarns2000 centrifugal pump with afterload pressure and those without afterload pressure were obtained by computational fluid dynamics(CFD). Results The velocity and flow of pump deceased when the rotational speed was 1 400 r/min with afterload pressure. The hemolytic blood damage increased with the pressure increase in the pump. However, the area whose surface shear force was greater than 150 Pa was less than 0.000032%, which had a good performance of hemolysis. Conclusion The afterload pressure would enhance the possibility of hemolysis in Sarns2000 centrifugal pump, while the surface shear force has a good performance of hemolysis.

Key words: computational fluid dynamics, centrifugal pump, numerical simulation, hemolysis