Journal of Shanghai Jiao Tong University (Medical Science) >

2013 , Vol. 33 >Issue 7: 1035

DOI: https://doi.org/10.3969/j.issn.1674-8115.2013.07.029

Review

Research progress of CCL7

  • HU Qing-xiang ,
  • QI Wen-xiao ,
  • ZHANG Xue-fei ,
  • et al
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  • 1.School of Clinical Medicine, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China; 2.Experiment Teaching Center, Basic Medical College,
    Shanghai Jiaotong University, Shanghai 200025, China

Online published: 2013-08-22

Supported by

Shanghai College Student Innovation Research Program, 2012020

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Abstract

Chemokine (C-C motif) ligand 7 (CCL7) is widely expressed in fibroblasts, monocytes and tumor cells, and exerts a spectrum of functions as monocyte recruitment, elicitation of calcium influx and facilitation of tumor metastasis via its interaction with specific receptors of CCR1, CCR2 and CCR3. This review will represent the up-to-date findings of CCL7 on its genetic and molecular structure, physiologic function, and its correlation with diseases.

Key words： chemokine (C-C motif) ligand 7; gene; molecular structure; tumor

Cite this article

HU Qing-xiang , QI Wen-xiao , ZHANG Xue-fei , et al . Research progress of CCL7[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2013 , 33(7) : 1035 . DOI: 10.3969/j.issn.1674-8115.2013.07.029

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