Advances of GPRC6A and its regulation function of glucose homeostasis
Online published: 2015-01-29
Supported by
National Natural Science Foundation of China, 81170788
The G protein coupled receptor family C, group 6, subtype A (GPRC6A) is a newly identified G protein coupled receptor, which involves in a broad range of physiological functions by combining with various ligands, such as calcium, basic amino acid, osteocalcin, and steroid, as well as the regulation of glucose homeostasis. Deletion of GPRC6A may cause disturbance of glucose homeostasis. Further study on GPRC6A and its regulation function of glucose homeostasis may identify a new therapeutic target for diabetes.
Key words: GPRC6A; glucose homeostasis; G protein coupled receptor; osteocalcin
DU Jing , BAO Yu-qian . Advances of GPRC6A and its regulation function of glucose homeostasis[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2015 , 35(1) : 128 . DOI: 11.3969/j.issn.1674-8115.2015.01.025
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