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Advances of GPRC6A and its regulation function of glucose homeostasis

  • DU Jing ,
  • BAO Yu-qian
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  • Department of Endocrinology and Metabolism, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai 200233, China

Online published: 2015-01-29

Supported by

National Natural Science Foundation of China, 81170788

Abstract

The G protein coupled receptor family C, group 6, subtype A (GPRC6A) is a newly identified G protein coupled receptor, which involves in a broad range of physiological functions by combining with various ligands, such as calcium, basic amino acid, osteocalcin, and steroid, as well as the regulation of glucose homeostasis. Deletion of GPRC6A may cause disturbance of glucose homeostasis. Further study on GPRC6A and its regulation function of glucose homeostasis may identify a new therapeutic target for diabetes.

Cite this article

DU Jing , BAO Yu-qian . Advances of GPRC6A and its regulation function of glucose homeostasis[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2015 , 35(1) : 128 . DOI: 11.3969/j.issn.1674-8115.2015.01.025

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