Journal of Shanghai Jiao Tong University (Medical Science) >

2015 , Vol. 35 >Issue 9: 1384

DOI: https://doi.org/10.3969/j.issn.1674-8115.2015.09.028

Review

Research advances of structural proteins of sperm flagella

  • SONG Ping-ping ,
  • ZOU Sha-sha ,
  • LI Zheng ,
  • et al
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  • Department of Urology， Renji Hospital， Shanghai Jiao Tong University School of Medicine， Shanghai 200001， China

Online published: 2015-09-30

Supported by

Foundation of Renji Hospital， Shanghai Jiao Tong University School of Medicine， RJZZ14-017； National Natural Science Foundations of China， 30973069， 30672146

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Abstract

The flagellum is the motility organ of mature sperms and its microtubule based axoneme structure is highly conservative during evolution. The defect or missing of sperm flagella protein, which is relevant to the structure and function of sperms, can lead to motility dysfunction of sperms and cause male infertility. This paper reviews the latest research advances of molecules relevant to the formation and motility of sperm tails. Problems of structure and function of these molecules are closely related to many clinical diseases.

Key words： sperm; flagellum; motility; protein

Cite this article

SONG Ping-ping , ZOU Sha-sha , LI Zheng , et al . Research advances of structural proteins of sperm flagella[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2015 , 35(9) : 1384 . DOI: 10.3969/j.issn.1674-8115.2015.09.028

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