Journal of Shanghai Jiao Tong University (Medical Science) >

2015 , Vol. 35 >Issue 10: 1581

DOI: https://doi.org/10.3969/j.issn.1674-8115.2015.10.030

Application of resting-state functional magnetic resonance imaging to exploring connectivity of brain network of patients with obsessive compulsive disorder

  • ZHAO Qing ,
  • HU Hao ,
  • WANG Zhen
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  • Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai200030, China

Online published: 2015-12-22

Supported by

Medicine Guidance Project of Science and Technology Commission of Shanghai Municipality,124119a8601; Biomedical Engineering Cross Research Foundation of Shanghai Jiao Tong University, YG2013MS65; National Key Clinical Disciplines at Shanghai Mental Health Center, OMA-MH 2011-873

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Abstract

Obsessive compulsive disorder (OCD) is a chronic disabling mental illness. Researches have revealed the abnormal connectivity of brain network. Resting-state functional magnetic resonance imaging (R-fMRI) is a powerful tool to explore the pathogenesis of OCD and other mental disorders. Seed-based analysis of interested region, independent component analysis (ICA), and graph theory-based analysis are popular methods to quantify brain network by R-fMRI data. This paper reviews current studies on connectivity of brain network of OCD by above methods and research progresses.

Key words： resting-state functional magnetic resonance imaging; obsessive compulsive  ; disorder; region of interest; independent component analysis; graph theory

Cite this article

ZHAO Qing , HU Hao , WANG Zhen . Application of resting-state functional magnetic resonance imaging to exploring connectivity of brain network of patients with obsessive compulsive disorder[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2015 , 35(10) : 1581 . DOI: 10.3969/j.issn.1674-8115.2015.10.030

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