Lymph node metastasis and staging of pancreatic adenocarcinoma are the most important factors for analyzing the prognosis of patients who underwent pancreaticoduodenectomy and have important clinical significance. There has been debated on the extent of lymphadenectomy during pancreaticoduodenectomy. Results of evidence based medicine researches show that extended lymphadenectomy has little positive effect on the post-operative survival of patients with pancreatic cancer. No studies support the extended lymphadenectomy according to recurrence and metastasis of pancreatic cancer and the survival quality of patients. This paper reviews the standardized surgical treatment of patients with pancreatic adenocarcinoma.