Advances of diagnosis and treatment of androgen insensitivity syndrome
Online published: 2016-01-21
Androgen insensitivity syndrome is a disease of sexual abnormality. The major cause is the mutation of androgen receptor gene. The karyotype is 46, XY. The syndrome is male pseudohermaphroditism and clinical manifestations are different levels of women posture changes and significant decrease of fertility, which remarkably affect the quality of life and mentality of patients. At present the treatment of patients with this syndrome is the comprehensive treatment based on sex assignment. This paper reviews advances of diagnosis and treatment of androgen insensitivity syndrome with the purposes of increasing the rate of early diagnosis, facilitating individualized and multidisciplinary therapies, and improving patients' quality of life.
ZHANG Mei-ying , DI Wen . Advances of diagnosis and treatment of androgen insensitivity syndrome[J]. Journal of Shanghai Jiao Tong University (Medical Science), 2015 , 35(12) : 1900 . DOI: 10.3969/j.issn.1674-8115.2015.12.026
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